Introduction: Odontogenic myxomas are benign but locally aggressive neoplasms arising from odontogenic ectomessenchyme found almost exclusively in the jaws and arise only occasionally in other bones.

Case report:.By a brief review of clinical and radiological features, and also diagnostic and operative dilemmas in assessment a rare case of adontogenic myxoma was presented, which was occurred in the mandible of a 26-year-old femal palient.

Conclusion: Careful evaluation of clinical features and radiographic imaging with detailed assessment of histpathology leads to correct diagnosis